Introduction : Intrahepatic cholestasis in pregnancy (ICP) is a Clinicopathological condition which carries increased fetomaternal morbidity and perinatal mortality. Prevalance of ICP varies from 1-20% according to various studies. This study was carried out in Deptt. of Obstt. & Gynaecology, CSMMU, Lko. collaboration with deptt. of Pathology from August 2006 to July 2007. Aims & objective : To study prevalence, Clinicopathological profile in cases of ICP and fetomalernal out come.