Objective : PCOS is an enigmatic disease. Though the pathophysiology is getting clearer, and hyperinsulinimia is found to be the key factor in the aetiopathogenesis, there are very few options of treatment. The present study addresses two questions, does the present treatment options available give a permanent cure, and what are the long term sequelae if any. Material and Methods : This is a well-controlled prospective study of 161 cases of PCOS.