Recurrent pregnancy loss (RPL) is defined as the occurrence of 3 or more clinically recognised pregnancy loses before 20 weeks, with incidence of 1.4%. Of the several causes the only undisputed causes being autoimmune disease (APA SYNDROME) and chromosomal diseases. AIM : 1. To study the effects of therapeutic interventions given to improve the outcome in women with RPL. 2.To study the obstetric course of women with history of RPL treated with these therapeutic interventions. Material And Methods : Study conducted on 36 pre-conceptional and 44 post-conceptional patients with history of RPL attending our OPD at BIMS Hospital Belgaum. between Jan 2006-Jan 2008.