Objective : To evaluate the efficacy of pap smear,HPV DNA testing,colposcopy and cervical biopsy in early diagnosis of cervical cancer. Methods : Four hundred non pregnant non-hysterectomised women between 30-60 years of age were studied and a detailed history was taken followed by gynecological examination.Women with vaginitis were excluded from the study.Four hundred women were subjected to pap smear examination.Selected patients were followed by HPV DNA testing by Hybrid CaptureII method,colposcopy and biopsy.Sensitivity,specificity,diagnostic accuracy and kappa value were calculated for each screening test Result : Out of four hundred women undergoing pap smear examination,50 had…