Objectives : To compare efficacy and safety of 50µgm vaginal misoprostol with oral misoprostol for labor induction. Methods : One hundred and ten women at term gestation, Bishop score < 4, with various indications for labor induction were double blinded and randomized. After decoding 51 women had received active drug (misoprostol) orally and 52 vaginally. The doses were repeated every 4 hourly (maximum 6 doses) or till women went into active labor. Main outcome Measures: Induction active labor interval, induction delivery interval, need for oxytocin augmentation, successful induction.