1st International Conference on Recent Advances in Anaesthesiology (INCRAA - 2009), 30 Jan – 01 Feb 2009 · Nehru Auditorium, AIIMS New Delhi

Background: Ventilator-associated pneumonia (VAP) is the most frequently occurring nosocomial infection associated with increased morbidity and mortality and may be influenced by oral health.We hypothesized that oral decontamination with either 0.2% chlorhexidine gluconate solution or H2O2 in Normal Saline in the ratio of 1:8 would reduce the incidence of VAP and oropharyngeal colonization. Objectives: To compare the effect of oral decontamination with 0.2% Chlorhexidine Gluconate solution Vs H2O2 solution on the incidence Of Ventilator Associated Pneumonia (VAP) in mechanically ventilated patients. Methods: A prospective, randomized, controlled clinical trial design was used.