1st International Conference on Recent Advances in Anaesthesiology (INCRAA - 2009), 30 Jan – 01 Feb 2009 · Nehru Auditorium, AIIMS New Delhi

Although anaesthesia has become much safer over the years, it is still not perfect. The introduction of propofol in the 1980s and subsequent development of TCI was a major breakthrough. The development of remifentanil has now also given us an alternative to nitrous oxide. Besides this, however, there have been disappointingly few new drug developments in anaesthesia. A number of new formulations of propofol have been developed in an attempt to reduce its side effects (propofol infusions are associated with acidosis and multi-organ failure in children and occasionally in adults).