Introduction(s) : Postmenopausal bleeding is an entity which alerts the patient as well as the gynaecologist for some untoward change towards the worst. Objective(s) : Was to correlate clinical profile and histopathological changes in endometrium for deciding the management strategy for these elderly women. Material and Method(s) : This prospective study was done on 60 postmenopausal women admitted in Obstetrics and Gynaecology Department of SMS Medical College, Zenana Hospital, Jaipur ftom April 2006 to March 2008. Endometrial sample was collected by dilatation and curettage in all cases. Histopathological findings were analysed and correlated with the clinical profile of the patient.