Objective : To compare the efficacy of prophylactic Diclofenac suppository (lOOmg) versus oral Ibuprofen (400mg) for effective analgesia following perineal injury during childbirth. To determine whether the analgesic effect was maintained beyond the first 24 hours postpartum. To know if the rectal route was acceptable to the women and whether there were any significant side effects. Methods : A double blinded randomized clinical trial was carried out on 200 women over one year period at KLEs Prabhakar Kore hospital Belgaum. Women having spontaneous vaginal delivery at term with either an episiotomy or second degree perineal tear were enrolled in the study.