All India Congress of Obstetrics & Gynaecology, 04–08 Jan 2009 · Birla Auditorium, Jaipur

Objective : To compare the safety and effectiveness of vaginal Misoprostol with combined vaginal Misoprostol and estradiol for induction of labor in unfavourable cevix. Method : A prospective study was carried out from Jan 2008 to Jul 2008 on total of 90 women with unfavorable cervix (Bishop's score was < 5) and gestation >36 wks with clinical indication for induction of labor. They were randomly assigned to receive either vaginal Misoprostol 25pg alone or vaginal Misoprostol 25 gg with vaginal estradiol 50Ag. Misoprostol 25[tg alone was repeated every 3 hours in both groups till ripening of cervix (Bishop's score was > 8 ) and establishment of active labor.